The Center for Macromolecular Interactions (CMI) is a biophysical instrumentation facility for the characterization of macromolecules and their interactions. The CMI mission is to enhance basic research in the HMS community by providing scientific consultation, training, and access to shared biophysical instruments. The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) and Dynamic Light Scattering (DLS), and MicroScale Thermophoresis (MST).
With Protein Thermal Shift Software.
NanoTemper Technologies Prometheus NT.Plex
Wyatt Dawn Heleos Multi-Angle Light Scattering detector, Wyatt in-line QELS (DLS) detector, Wyatt Optilab TrEX Refractive Index detector, Agilent Infinity 1260 Analytical Size Exclusion Chromatography System with UV and fluorescence detectors