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Center for Human Genetic Research

Director: Gusella, James, Ph.D.

Location: Simches Building, Suite 2000, 185 Cambridge Street, Boston, MA 02114


The Center for Human Genetic Research (CHGR) is a multidisciplinary cross-departmental center whose central mission is promotion of the genetic research cycle.





  • Beagle Genome Annotation Database ( Database )

    "Beagle is a human-centered database designed as a tool for biological discovery and exploration. The 2.4 GB database, which includes build-in software, has records for all ~245,000 Homo sapiens, Pan troglodytes, Canis lupus familiaris, Mus musculus, Danio rerio, Drosophila melanogaster, Caenorhabditis elegans, Saccharomyces cerevisiae, and Schizosaccharomyces pombe genes. Gene records provide links to paralogs, to members of gene families, to genes sharing various functions, and to genes whose encoded proteins share various conserved domains. The database also identifies orthologs and organizes information on ~0.5 million physical, transcriptional, genetic, functional, microarray, and miRNA interactors. Records include gene-specific hyperlinks to multiple online databases, allowing Beagle to serve as a versatile 'data hub'. A 'Guided tour' file provides a more detailed description of the database and its various functions."

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Last updated: 2012-11-28T15:10:55.938-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016