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Harvard Chan Bioinformatics Core (HBC)

Director: Ho Sui, Shannan, Ph.D.

Location: Department of Biostatistics, Landmark Center, Level 3 East, 401 Park Drive, Boston MA 02215


The Harvard Chan Bioinformatics Core (HBC) offers consultations on basic questions in research computing, bioinformatics, and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise.

Core staff support researchers within the Harvard community throughout the scientific life cycle, on issues such as:
● experimental design and methods development
● grant support and development of manuscripts
● data quality assessment and analysis





  • Consulting ( Support service )

    Provides assistance in the bioinformatic analysis of experimental data, with a focus on next-generation sequencing (NGS), including:
    ● Variant sequencing (exome, whole-genome, and targeted)
    ● RNA-seq (bulk, small RNA, single-cell/nuclei)
    ● Epigenetic assays (ChIP-seq, ATAC-seq, and bisulfite sequencing)
    ● Functional interpretation of results from NGS experiments

  • Training ( Training service )

    Provides bioinformatics training through workshops focused on experimental design, data management, basic data skills, and NGS data analysis.

    ○ Command-line interface
    ○ Cluster computing
    ○ R statistical programming language

    ○ Bulk RNA-seq
    ○ Single-cell RNA-seq
    ○ ChIP-seq

    Best practices for research, rigor and reproducibility

    More information about training events can be found at https://bioinformatics.sph.harvard.edu/training, and training materials can be accessed from https://hbctraining.github.io/main

Web Links:

Last updated: 2020-04-09T11:10:43.624-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016