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Specialized Histopathology Services Core (DF/HCC)

Directors: Aster, Jon Christopher, M.D., Ph.D. (Longwood site); Stemmer-Rachamimov, Anat O., M.D. (MGH site)


Tissue analysis is critical to validation and evaluation of animal models of human cancer, and human cancer tissues serve as the "operating system" for translational research. The facility supports a wide spectrum of cancer-relevant research, from basic studies on pathogenic mechanisms in cancer to translational research focused on the development of new tests for biomarkers that stratify patients and direct therapy.

The Specialized Histopathology (SHP) Core has two performance sites: Longwood, Directed by Jon Aster and based at the Brigham and Women’s Hospital and MGH, Directed by Anat Stemmer-Rachamimov and based at Massachusetts General Hospital East in Charlestown.

The SHP Core provides high-quality, timely, state-of-the-art technical and professional pathology services to investigators working in a variety of experimental organisms, including rodents, fish, and monkeys, as well as with human tissues. The Core performs routine histology and special histochemical stains, and also assists in experimental design and the development, application, and interpretation of biomarker tests and their results. Specific services include immunohistochemistry, immunofluorescent staining, and in situ hybridization.

Performance Sites:
Specialized Histopathology Services- Longwood Core
Brigham and Women's Hospital
75 Frances Street, Thorn 604, 603b
Boston, MA 02115

Specialized Histopathology Services- MGH Core
Massachusetts General Hospital-East
13th Street, Building 149
Charlestown Navy Yard 6, Room 6122
Boston, MA 02129



    Member: Bowman, Teri
    Role: Core Manager, Handles Technical Questions and General Inquiries for all Core Services
    Phone: (617) 525-9394

    Member: Gianatasio, Marie
    Role: MGH Core Manager, Handles Technical Questions and General Inquiries for All Core Services
    Phone: (617) 726-5510

    Member: Wyner, Lauri
    Role: Content Manager
    Phone: (617) 432-4947



Web Links:

Last updated: 2019-01-07T14:23:14.337-05:00

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