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Center for Crystallographic Studies (FAS)

Location: 12 Oxford Street, Bauer 05-06, Cambridge, MA 02138


The X-ray diffraction facility in Harvard University offers single crystal X-ray data collection, structure solution and refinement of small molecule structures.






  • Access to X-Ray Facility instrumentation ( Access service )

    "The X-Ray facility strongly encourages participation by the users in the structure determination, refinement and graphics interaction of molecular structure determinations. Users who wish to participate in single-crystal structure determination (DIY users) are free to do so if they have undergone the appropriate training."

  • Cambridge structural database access ( Access service )

    The CSD is available to registered users of the laboratory and is accessed on the laboratory's PC and in the Department's Library. The Cambridge Structural Database contains bibliographic, 2D chemical and 3D structural results for organocarbon compounds studied by X-ray or neutron diffraction.

  • Charge density analysis ( Material analysis service )

    Charge density work includes: ultra-high resolution, low-temperature data collection; multipole refinement; and charge density analysis combined with theoretical calculations.

  • Crystal mounting service ( Material processing service )

  • Inorganic crystal structure database access ( Access service )

    Comprehensive compilation of crystal structure data of inorganic compounds distributed by GMELIN-Institut and Fiz Karlsruhe.

  • Macromolecular X-ray diffraction service ( Material analysis service )

    "The laboratory uses the instrument provided by the Harvard Department of Molecular and Cellular Biology. This instrument includes a state-of-the-art R-AXIS area detector system. Permission for use or services are granted through Prof. Rachelle Gaudet."

  • Protein data bank access ( Access service )

    The database is home to the single world wide repository for the processing and distribution of 3-D biological macromolecular structure data.

  • Single-Crystal service ( Material analysis service )

    "Crystal quality is probably the single most important factor in determining the final precision for a given x-ray structural investigation. High precision structural result requires high-quality crystals. In general, crystals for an x-ray study must be single and of the proper size and shape. The crystal can usually be analyzed in-house if they are at least 0.05 mm thick in two dimensions. Micro-sized crystals that are difficult to get reasonable resolution data could be analyzed by using synchrotron radiation at the Advanced Photon Source."

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Last updated: 2013-04-29T13:51:31.373-04:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016