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ICBG 10 - Sherman Lab Extracts

eagle-i ID

http://harvard.eagle-i.net/i/0000012c-3c83-8302-6d7a-cc8780000000

Resource Type

  1. Natural product extracts chemical library

Properties

  1. Library Source
    ICCB-Longwood Screening Facility (HMS)
  2. Resource Description
    384-well plate format. Concentration Information: 15mg/mL. This library was plated and added to the collection in November 2008. Production of this library was funded by an International Cooperative Biodiversity Groups (ICBG) grant from the NIH to Dr. Jon Clardy (Harvard Medical School) and to Dr. David Sherman (University of Michigan). The library contains partially purified extracts. Crude extracts from marine bacteria, actinomycetes and cyanobacteria were fractionated to eliminate nuisance compounds, especially those of high molecular weight or high polarity. Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy. Please contact Caroline Shamu to arrange for purification of "hit" compounds from extract samples.
  3. Contact
    Shamu, Caroline, Ph.D.
  4. Manufacturer
    Clardy, Jon
  5. Access Restriction(s)
    Please note that ICCB-L provides these reagents only within the context of a full screen or an approved medicinal chemistry project.
  6. Website(s)
    https://iccb.med.harvard.edu/retired-libraries
  7. Library Count
    1,787 compounds
  8. Location
    ICCB-Longwood Screening Facility (HMS)
 
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