In vitro assays to validate drug target specificity

eagle-i ID

Resource Type

Properties

1. Fee for service

   Yes

2. Resource Description

   Service includes: the design and implementation of in vitro assays to validate target specificity; target validation of agents or combinations of agents in cell culture in one or more murine and human tumor cell lines or mouse embryonic fibroblasts (MEFs) of various genotypes; use of several different assays depending upon the agent and type of information sought; availability of an extremely large number of genetically modified MEFs lines and human tumor cell lines in our frozen repository for these studies.

3. Contact

   0000012a-2519-e7f3-5617-794280000000

4. Access Restriction(s)

   Fees vary for academic internal, academic external and corporate fees.

5. Service Provided by

   Preclinical Murine Pharmacogenetics Core (BIDMC)

6. Website(s)

   http://bidmc.org/Research/CoreFacilities/PreclinicalMurinePharmacogeneticsCore/Services.aspx