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Non-Coding RNA Core Facility

Directors: Hide, Winston, Ph.D.; Slack, Frank J., Ph.D

Location: BIDMC East Building, ESB01A-H, 330 Brookline Avenue, Boston, MA 02215

Summary:

The ncRNA Core is a state-of-the-art informatics/sequencing/imaging/delivery/
preclinical facility dedicated to non-coding RNA at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS). We will offer the following services to all researchers:

1) Detection, quantification and discovery of ncRNAs including in research and clinical specimens
2) Specialized bioinformatics for interpretation of ncRNA discoveries
3) Precision delivery of ncRNA therapeutics to diseased tissue in vitro

The ncRNA Core is co-directed by Dr. Frank Slack, Director of the Harvard Medical School Initiative for RNA Medicine (HIRM). Established in 2014 as the Institute for RNA Medicine and hosted by the BIDMC Cancer Center, the HIRM brings together leading investigators in the field to accelerate investigations into how non-coding RNA functions and how these insights can be used to develop new therapies.

The ncRNA Core is situated in BIDMC space ESB01A-H, which is located in the basement of the BIDMC East Building at 330 Brookline Avenue in the Longwood Medical area of Boston.

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Instruments

  • Malvern Zetasizer ( Particle size analyzer )

    The Zetasizer provides both exceptionally high performance and entry level systems that incorporate combinations of a particle size analyzer, zeta potential analyzer, molecular weight analyzer, protein mobility and microrheology measurements. Particles and molecules from less than a nanometer in size to several microns can be analyzed.

  • NanoAssemblr Benchtop ( Instrument )

    Midi-prep device for making sufficient quantities of nanoparticles for in vitro testing.

  • NanoAssemblr Blaze ( Instrument )

    Midi-prep device for making sufficient quantities of nanoparticles for in vitro testing.

  • NanoAssemblr Spark ( Instrument )

    Mini-prep system for creating custom lipid nanoparticles (LNPs) for target delivery testing.

Services


Web Links:

Last updated: 2019-05-09T10:04:48.007-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016