The Center for Macromolecular Interactions (CMI), is a biophysical instrumentation facility for the characterization of macromolecules and their interactions. The CMI mission is to enhance basic research in the HMS community by providing scientific consultation, training and access to shared biophysical equipment. The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), and Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS).
With Protein Thermal Shift Software.
Agilent Infinity 1260 Analytical Size Exclusion Chromatography System with UV and fluorescence detectors
Wyatt DAWN Heleos II Multi-Angle Light Scattering (MALS) detector and OptiLab TrEX Refractive Index detector