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Harvard Catalyst Clinical Research Center

Director: Pascual-Leone, Alvaro, Ph.D., M.D.

Summary:

The Harvard Catalyst Clinical Research Center (HCCRC) provides state-of-the-art clinical research facilities and expertise to faculty who conduct human studies.

For a comparison table of offerings at the five HCCRC sites, as well as details and contact information for each site, see: http://catalyst.harvard.edu/programs/hccrc/hccrc-sites.html

Affiliations:

People:

Resources:

Instruments

  • Automated BP/HR/O2 Sat/RR/ECG Device ( Multiparameter monitor )

    Used for patient monitoring during a study. It will monitor the blood pressure, pulse, oxygen saturation of the blood, respirations and can also do ongoing EKG monitoring.  You can use all of some of the features, and can set for the frequency of monitoring as needed.

  • Bioeletrical Impedance Analysis (BIA) ( Body fat meter )

    Measures electrical conductivity to indirectly assess body composition.

  • BodPod ( Plethysmograph )

    An instrument used to assess body composition by air displacement plethysmography (volume).

  • Body temperature monitor ( Temperature monitor )

    Electronic sensor for core body or skin temperature collection over several hours.

  • Calorimeter ( Calorimeter )

    The process of measuring the heat of chemical reactions or physical changes as well as heat capacity.

  • Cycle Ergometer ( Ergometer )

    Use of a stationary bike to assess exercise tolerance/capacity.

  • Dental chair and Periotron ( Dental instrument )

    A dental engine serving as a source of mechanical or pneumatic power for one or more hand pieces. The Periotron is designed to quantify submicrolitre volumes of fluid sampled on a filter paper strip

  • DXA scanner ( Bone densitometer )

    Measures bone mineral density and body composition.

  • ECG device ( ECG monitor )

    Device to measure electrical activity of the heart.

  • Glucose, Glucometer ( Glucometer )

    Instrument that measures blood glucose at the bedside.

  • Peripheral Quantitative Computed Tomography (pQCT) ( Instrument )

    Scanner to assess bone density

  • Physio Equipment ( Monitoring device )

    Physiological monitoring equipment is used to monitor vital physiologic parameters so that clinicians can be informed of changes in a patient's condition.

  • Refrigerated centrifuge ( Refrigerated centrifuge )

    Centrifuge for sample processing; maintained at 4 degrees.

  • Room temperature centrifuge ( Centrifuge )

    Centrifuge for sample processing; maintained at room temperature.

  • Syringe infusion Pump ( Syringe pump )

    Device for automatic intravenous medication administration via syringe.

  • Treadmill ( Treadmill )

    Use of a treadmill to assess exercise tolerance, i.e. modified Bruce protocol.

  • Ultrasound device ( Ultrasound machine )

    Device that uses sound waves that are reflected differently by body tissues to create a picture of the inside of the body.

  • Vitaport ( Digital sleep recorder )

    Computer collection device for EEG/PSG recordings.

Services

  • "Off unit" research support ( Support service )

    Nursing, Registered Dietitians and lab technicians are available to perform off-unit visits and to support clinical research activity in other areas of the institution and in the community

  • Anthropometry ( Analysis service )

    A technique that deals with the measurement of the size, weight, and proportions of the human body

  • Assess for AE & SAE ( Service )

    Assess for adverse effects and severe adverse effects

  • Controlled environment test areas ( Access service )

    For specialized studies such as sleep and neurologic testing.

  • Dedicated research space ( Access service )

    In-patient and out-patient facilities dedicated to the conduct of clinical research.

  • Diet Assistant/Tech service ( Access service )

    A nutrition staff member specifically trained in nutrition research skills and techniques.

  • Experienced patient care research staff ( Support service )

    Includes: 1) nurses, nurse practitioners and technicians to perform research procedures and precise research measurements, and 2) expertise in standard and investigational drug delivery and clinical monitoring.

    The research center nursing staff is specially trained to provide the following services:

    - Assist investigators with the planning and implementation of clinical research protocols; develop data collection sheets and MD orders.
    - Perform clinical assessments, observations, and treatments.
    - Provide patient care while adhering to the detail of research protocols.
    - Collect and maintain the integrity of research specimens.
    - Process research specimens using basic techniques.
    - Advocate for subjects and their families who are volunteering to participate in research.
    - Monitor, identify, and report adverse events.
    - Research nurse coordinators can assist with study coordination either alone or in concert with study coordinators.

  • Food record analysis ( Analysis service )

    Based on specific aims, the RDs can help investigators select the appropriate tools (e.g., food intake records, diet histories, food frequency questionnaires) to collect and analyze nutrient intake data.

  • Inpatient unit ( Access service )

    A compilation of rooms varying at each site accommodating longer, more complicated studies.

  • Lab Assistant/Tech service ( Material processing service )

    Lab processor; often has BS degree in health sciences and has training in common lab processes for preparation of samples.

  • Laboratory Services ( Material analysis service )

    - Specimen processing; assay research analytes in patient specimens.
    - Assistance with/payment of routine laboratory testing at centralized contract laboratory.

  • Medical Research Officer ( Support service )

    Person (MD) who provides guidance for study planning to investigators, and clinical oversight for research protocols.

  • Metabolism & Nutrition Research (MNR) ( Analysis service )

    Registered Dietitian specifically trained in nutrition research skills and techniques.

  • Nurse Practitioner, family ( Support service )

    An RN most often with a Bachelors degree. Able to carry out patient specific treatments, administer Physiological assessments, medications, draw blood, start IVs, while assessing the patient’s health status. Works as part of an interdisciplinary team. Able to treat patients in all stages of life (birth to death).

  • Nurse Practitioner, other ( Support service )

    An RN who has advanced education (Masters or Doctorate degree) and is able to diagnose and treat common health conditions, as well as prescribe medications.

  • Nursing research ( Support service )

    An RN most often with a Bachelors degree. Able to carry out patient specific treatments, administer Physiological assessments, medications, draw blood, and start IVs, while assessing the patient’s health status. Works as part of an interdisciplinary team.

  • Outpatient rooms ( Access service )

    A variety of exam, consult and specialized rooms within each site to be used by investigators.

  • Patient Care Assistant/Tech service ( Support service )

    An unlicensed staff member who works with RN to assist in patient care.  Can take vital signs, do EKGs, single stick blood draws.  Basic skills under supervision of RN.

  • Pediatric/neonatal research ( Support service )

    Research addressing clinical issues affecting pediatric and neonatal patients.

  • Phlebotomist ( Material processing service )

    Technical staff who can draw blood via single stick.

  • Psychometrician ( Analysis service )

  • Research assistance where the research encounter occurs ( Support service )

    Research nurses, research dietitians, and study coordinators who travel to clinical sites within the hospital such as ED, ICUs, Cardiology, Radiology, specialized units such as BMT, etc.

  • Research study coordinator/Project management services ( Support service )

    A staff member responsible for conducting various aspects of a research study under a Principal Investigator.

  • Specialized physiological monitoring ( Support service )

    Monitor vital physiologic parameters so that clinicians can be informed of changes in a patient's condition.

  • Specialized research equipment ( Access service )

    State-of-the-art equipment for physiological monitoring and research testing.

  • Specimen processing ( Material processing service )

    LabCorp offers centralized laboratory analysis of a wide array of routine analytes in real time. Results are available within 24 hours from sample pickup. If results are needed sooner to allow the research to proceed, the investigator may use their hospital lab for analysis

  • Specimen storage ( Storage service )

    Freezers for specimen storage are available. Investigators can store specimens until a full batch has been collected for analysis.

  • Ultrasound Assistant/Tech service ( Material analysis service )

    A registered sonographer that operates ultrasonic imaging devices to produce images, scans, videos, of 3D volumes of anatomy and diagnostic data.

  • Weighed/controlled meal preparation ( Support service )

    A prepared meal that requires a gram scale for weighing food items based on an individualized nutrient controlled diet.

    Meal plans are calculated to meet specific nutrient levels defined by the research protocol. Meal plans can be controlled for macronutrients (e.g., carbohydrate, protein, fat) and/or micronutrients (e.g., sodium, potassium, magnesium), glycemic index, or other study specifications. In order to maintain an exact nutrient intake, subjects must finish all food provided to them. No additional food or beverage intake is allowed. Specific meal plans can be developed for meal challenges or test meals.

  • Weighed/controlled snack preparation ( Support service )

    A prepared snack that requires a gram scale for weighing food items based on an individualized nutrient controlled diet.

    Meal plans are calculated to meet specific nutrient levels defined by the research protocol. Meal plans can be controlled for macronutrients (e.g., carbohydrate, protein, fat) and/or micronutrients (e.g., sodium, potassium, magnesium), glycemic index, or other study specifications. In order to maintain an exact nutrient intake, subjects must finish all food provided to them. No additional food or beverage intake is allowed. Specific meal plans can be developed for meal challenges or test meals.


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Last updated: 2015-02-27T09:05:35.980-06:00

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