Our laboratory is a multinational group located at Children's Hospital Boston. We study development, cellular reprogramming, disease processes, and the improvement of therapeutics with an emphasis on leukemia and genetic blood disorders. These projects build upon basic studies of pluripotent stem cells, the development of blood-forming or hematopoietic tissue, epigenetic regulation, and mechanisms of cancer initiation, progression, and therapy resistance.
Cell Line: CHB-1
NIH Registration Number: 0001* On Hold (see note below)
NIH Approval Number: NIHhESC-09-0001
* On Hold - NIH has received public comment on a proposed change to the definition of “human embryonic stem cells” in the NIH Guidelines for Human Stem Cell Research. While NIH is considering those public comments on the proposed change, this hESC line is currently on hold and should not be used in NIH-funded research. If grantees are currently using any of these lines they may contact the NIH Institute or Center that is funding their project for further information.
Cell Line: CHB-10
NIH Registration Number: 0009
NIH Approval Number: NIHhESC-09-0009
Cell Line: CHB-11
NIH Registration Number: 0010
NIH Approval Number: NIHhESC-09-0010
Cell Line: CHB-12
NIH Registration Number: 0011
NIH Approval Number: NIHhESC-09-0011
Cell Line: CHB-2
NIH Registration Number: 0002
* On Hold (see note below)
NIH Approval Number: NIHhESC-09-0002
* On Hold - NIH has received public comment on a proposed change to the definition of “human embryonic stem cells” in the NIH Guidelines for Human Stem Cell Research. While NIH is considering those public comments on the proposed change, this hESC line is currently on hold and should not be used in NIH-funded research. If grantees are currently using any of these lines they may contact the NIH Institute or Center that is funding their project for further information.
Cell Line: CHB-3
NIH Registration Number: 0003
* On Hold (see note below)
NIH Approval Number: NIHhESC-09-0003
* On Hold - NIH has received public comment on a proposed change to the definition of "human embryonic stem cells" in the NIH Guidelines for Human Stem Cell Research. While NIH is considering those public comments on the proposed change, this hESC line is currently on hold and should not be used in NIH-funded research. If grantees are currently using any of these lines they may contact the NIH Institute or Center that is funding their project for further information.
Cell Line: CHB-4
NIH Registration Number: 0004
NIH Approval Number: NIHhESC-09-0004
Cell Line: CHB-5
NIH Registration Number: 0005
NIH Approval Number: NIHhESC-09-0005
Cell Line: CHB-6
NIH Registration Number: 0006
NIH Approval Number: NIHhESC-09-0006
Cell Line: CHB-8
NIH Registration Number: 0007
NIH Approval Number: NIHhESC-09-0007
Cell Line: CHB-9
NIH Registration Number: 0008
NIH Approval Number: NIHhESC-09-0008