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HSDM Micro CT Core

Director: McBride, Jim

Location: 188 Longwood Avenue, REB 316, Boston, MA 02115

Summary:

The Harvard School of Dental Medicine under the direction of The Office of Research operates a core facility composed of two micro CT machines.

Affiliations:

People:

Resources:

Instruments

  • SCANCO µCT 35 ( Computed tomography scanner )

    "µCT 35 offers high resolution on the desktop. The optional sample changer accommodates up to 8 sample holders."

  • Xradia MicroXCT-200 ( Computed tomography scanner )

    "The MicroXCT-200 is a versatile 3D X-ray imaging system suited for non-destructive analysis of a large variety of samples. Its unique design allows for high resolution imaging for relatively large samples. Its detectors are tailored to image both high and low absorption materials. The MicroXCT-200 provides the unique high resolution 3D imaging ability that allows analysis and visualization of internal fine 3D structures in intact samples, which is not possible with typical surface analysis tools like the AFM, SEM or conventional CT systems."

Services

  • Mouse Long Bone Scans ( Material analysis service )

    "Time: 1 hour will be charged per long bone, this type of scan includes the following:

    * Scan time on the Scanco uCT 35
    * Image reconstruction / processing
    * Standard sample analysis

    The parameters reported during a typical long bone scan include:

    * BV/TV [1] – A ratio of bone volume to total volume
    * Tb.N [mm] - Trabecular number
    * Tb.Th [mm] - Trabecular thickness
    * TB.Sp [mm] - Trabecular separation
    * M.BV/TV [1] – A ratio of bone volume to total volume in the medullary of the long bone.
    * C.Th [mm] – Cortical thickness

    Data will be reported as an Excel spreadsheet. We will also produce standard images of both scanned regions. Non-standard images will be produced for a fee per hour of technical assistance and processing time."

  • Mouse Vertebrae Scans ( Material analysis service )

    "Time: 1 hour will be charged per vertebrae, this type of scan includes the following:

    * Scan time on the Scanco uCT 35
    * Standard sample analysis

    The parameter collected during a typical long bone scan include:

    * BV/TV [1] – A ratio of bone volume to total volume
    * Tb.N [mm] - Trabecular number
    * Tb.Th [mm] - Trabecular thickness
    * TB.Sp [mm] - Trabecular separation

    Data will be reported as an Excel spreadsheet. We will also produce standard images of both scanned regions. Non-standard images will be produced for a fee per hour of technical assistance and processing time."

  • Variable Analysis (all analysis not included in the standard long bone or vertebrae packages) ( Material analysis service )

    "Time: Variable depending on your project, please work with us to understand the requirements of your project. This includes:

    * Technician time
    * Computer processing time

    Possibilities:

    * Non-standard images
    * Simple videos
    * Complex videos
    * Custom quantification
    * More!

    Software Available

    * Scanco software (simple and segmented images and videos, simple / complex quantification)
    * Xradia software (simple images, simple videos)
    * Avizo Fire (Simple/complex images, simple/complex videos, simple/complex quantification)"

  • Variable Scans (All other than standard long bone and vertebrae scans) ( Material analysis service )

    "Time: Variable depending on your project, please work with us to understand the requirements of your project. This includes:

    * Technician time to load your sample and start the scan
    * Scan time on the Scanco uCT 35 or Xradia MicroXCT-200

    Does NOT include:

    * Analysis
    * Image reconstruction on the Xradia

    Analysis options:

    * Take data and use own software (ImageJ, etc.)
    * Internal users may be granted access to Avizo Fire or Scanco software for a limited time
    * See “variable analysis” for more options"

Software

  • Avizo Fire ( Software )

    "Avizo Fire offers a broad range of software tools for obtaining and visualizing advanced qualitative and quantitative information on material structure images.

    For industrial tomography, crystallography, material microstructure evolution, modality inspection for nano-structure, non destructive testing and evaluation, core sample analysis and surface analysis, food analysis. Avizo Fire delivers the whole feature set allowing materials scientists to see the invisible, and to understand and present their data."

    (Simple/complex images, simple/complex videos,
    simple/complex quantification)

  • Scanco MicroCT software ( Software )

    Used for variable analysis of simple and segmented images and videos; simple / complex quantification.

  • Xradia software ( Software )


Web Links:

Last updated: 2015-11-19T12:38:24.403-06:00

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