The HSPH Bioinformatics Core (HBC) offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise.
HBC has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts.
Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.
Provides assistance in the bioinformatic analysis of experimental data, with a focus on next-generation sequencing, including variant sequencing (exome and whole genome), RNA-seq (regular, splicing, small RNA, single cell) and epigenetic based (ChIP-seq and bisulfite sequencing).
Provides guidance and training on the selection and use of appropriate bioinformatic techniques and tools, including websites, databases, and software packages, by short courses, seminars and workshops.