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MGH Metabolic Imaging Core

Director: Torriani, Martin, M.D., M.SC.

Location: 55 Fruit St – YAW 6048, Boston, MA – 02114

Summary:

The MGH Metabolic Imaging Core offers specialized imaging techniques including quantitative computed tomography (QCT), magnetic resonance (MR) spectroscopy of muscle and high-resolution MR imaging. These techniques are employed for studies evaluating body composition and metabolic disorders of muscle, bone, marrow, cartilage and liver. The Core also performs imaging for anatomic and structural studies in humans, phantoms and cadaveric specimens.

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Instruments

Services

  • Magnetic Resonance Imaging (MRI) ( Material analysis service )

    MR imaging techniques are available for researchers requiring high-resolution imaging of joints, cartilage and soft tissues. Our staff provides expertise in design and implementation of imaging protocols.

  • Magnetic Resonance Spectroscopy (MRS) ( Material analysis service )

    Proton MRS allows non-invasive measurement of metabolites such as lipids, total creatine, and choline.
    - Proton MRS services of muscle (for measurement of intramyocellular and extramyocellular lipids, total creatine and choline)
    - Proton MRS of bone marrow (for measurement of marrow fat)
    - Proton MRS of liver (for measurement of hepatocellular lipids)

    Phosphorous MRS allows non-invasive assessment of muscle function through the measurement of metabolites such as phosphocreatine, ATP, ADP, inorganic phosphate and pH during rest, exercise and recovery.

    Our MRS data is acquired on GE or Siemens scanners at 1.5T or 3.0T field strengths and is analyzed with validated softwares such as LCModel and jMRUI.

  • Quantitative Computed Tomography (QCT) ( Material analysis service )

    QCT used for assessment of body composition (fat and muscle compartments) and bone mineral density.


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Last updated: 2014-05-12T15:38:32.225-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016