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Charles Weitz Laboratory

Summary:

We study the molecular biology and genetics of circadian clocks, endogenous oscillators that drive daily rhythms in behavior and physiology. Under natural conditions, circadian clocks become precisely synchronized, or entrained, to the 24-hour light-dark cycle by the action of light on circadian photoreceptors. Together the intrinsic rhythms of the circadian clock and its entrainment to light-dark cycles control the temporal organization of complex behavioral and metabolic programs. In flies and mammals, the master circadian clock regulating behavioral activity is located within specific clock cells in the brain. Of late it has become clear that multiple peripheral tissues in mammals contain circadian clocks, but the roles of peripheral clocks and their relationship to the central clock are not yet understood.

Affiliations:

People:

    Member: Liu, Ming
    Role: Associate in Neurobiology

Resources:

Organisms and Viruses

  • Bmal luciferase ( Mus musculus )

    It is used to study circadian rhythm.

  • Condition Bmal ( Mus musculus )

    It is used to study circadian rhythm.

  • stop Bmal ( Mus musculus )

    It is used to study circadian rhythm.


Web Links:

Last updated: 2011-05-17T13:55:12.835-05:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016